V937 employs the intercellular adhesion molecule I (ICAM-I, CD54) receptor for attachment and viral entry (Shafren et al., 1997a; 1997b); this receptor is overexpressed in numerous malignant cells, including melanoma (Kageshita et al., 1993; Hayes and Seigel, 2009). The gene discussed is ICAM1; the disease is melanoma.