PTH and osteoporosis: At present, the main mechanisms of osteoporosis drugs include inhibiting bone resorption, promoting bone formation, other mechanisms and traditional Chinese medicine, such as bisphosphonates, estrogen and parathyroid hormone (PTH), etc. However, long-term use of bisphosphonates can lead to jaw necrosis and atypical fractures of long bones (Hollick and Reid, 2011).