DLG4 and schizophrenia: Some schizophrenia- and autism-associated genes, such as DLG4 (disks large homolog 4, MIM 602887), DRD2 (dopamine receptor D2, MIM 126450), NOS1 (nitric oxide synthase 1, MIM 163731), NRXN1 (neurexin-1, MIM 600565), and SOX10 (sex-determining region Y-box 10, MIM 602229), have all been shown to have age-related dynamically methylated changes throughout the entire lifetime, especially in the fetal and postnatal stages (Numata et al., 2012).