In TCGA-BLCA cohort, Cox univariable analysis showed pathological stage (hazard ratio (HR) = 1.7618, p < 0.001), T stage (HR = 1.6423, p < 0.001), N stage (HR = 1.5524, p < 0.001), M stage (HR = 2,4975, p < 0.01) and SLC12A8 expression (HR = 1.5810, p < 0.001) influenced overall survival. This evidence concerns the gene SLC12A8 and bladder transitional cell carcinoma.