HSPD1 and non-small cell lung carcinoma: The results markedly indicated that HSPD1 knockdown cells formed very small and slower-growing tumors compared to control pLKO cells, in terms of both tumor volume and tumor weight (Fig. 3C-H), an effect which was maintained for the entire duration of the experiment, hence confirming that HSPD1 is required for NSCLC growth.