PVT1 and juvenile Huntington disease: In the current study, we observed significant alterations in abhydrolase domain containing 11, opposite strand (Abhd11os), Pvt1, Trp3cor1, Kalrn, linc-RNA activator of myogenesis (Linc-RAM), lncRNA chr10:69819062-69871640_F and Dino. Increased expression of Abhd11os has previously been shown to decrease lesion size in a Huntington’s disease mouse model and the authors reported its crucial roles in neurodegenerative diseases [90], but the exact mechanism is still unclear.