Laron dwarves, who have attenuated IGF‐1 signaling due to a defective GH receptor, have been shown to have lower rates of cancer, stroke, and diabetes (Guevara‐Aguirre et al., 2011), but may also suffer from obesity, auditory defects, and cognitive deficits (Laron & Kauli, 2016). The gene discussed is IGF1; the disease is obesity due to melanocortin 4 receptor deficiency.