IGF1 and cancer: In genetically modified knock‐down and knock‐out models, attenuated growth hormone (GH)/IGF‐1 signaling generally improves the health of mice, delaying age‐associated pathologies such as sarcopenia, immunosenescence, and cancer (Ikeno et al., 2009; Selman et al., 2008; Spadaro et al., 2016).