HK2 and Miyoshi myopathy: Comparative studies have suggested that WB-MRI is more sensitive than PET/CT for the detection of bone marrow infiltration at diagnosis of MM thanks to its high spatial resolution and sensitivity to diffuse infiltration and due to the lack of FDG uptake in a significant (10–15%) proportion of MM patients which is most likely due to a low hexokinase-2 expression [87, 111, 119, 120].