FOXO3 and neoplasm: Moreover, forkhead box O3 (FOXO3) was a tumour suppressor targeted by miRNA in human pancreatic cancer progression,13 while FOXO3a has been previously demonstrated to regulate BH3‐interacting domain death agonist (BID), which is a pro‐apoptotic protein belonging to the B‐cell lymphoma‐2 (Bcl‐2) protein family.14