To investigate whether LINC00472 could mediate FOXO3 to influence pancreatic cancer cell functions, LINC00472 was silenced in the pancreatic cancer cell BXPC3 overexpressing FOXO3, after which RT‐qPCR was conducted to determine the expression patterns of LINC00472, miR‐23a‐3p and FOXO3, while Western blot analysis was conducted to determine the protein expression pattern of FOXO3. This evidence concerns the gene LINC00472 and familial pancreatic carcinoma.