Indeed, compared with single treatment with anti‐PD‐1 (αPD‐1) or anti‐PD‐L1 (αPD‐L1) alone, the combination of αPD‐1 or αPD‐L1 with AIMS(EPT, R848, PTX) significantly increased the antitumor effect of ICB and increased the survival rate in two different tumor models (4T1 and TC1) (4T1; Figure 8b,e,f, TC1; Figure 8g,j,k). Here, CD274 is linked to neoplasm.