The antitumor effect was also greater when AIMS(EPT, R848, PTX) was combined with PD‐1(tumor free mice ratio was 37.5%) than when it was combined with PD‐L1(tumor free mice ratio was 12.5%), suggesting that blocking PD‐1 is better than blocking PD‐L1 after AIMS(EPT, R848, PTX) treatment. Here, CD274 is linked to neoplasm.