The data show that high PLAP expression is linked to advanced pT stage (p = 0.0086), nodal metastasis (p = 0.0085), and lymphatic (p = 0.007) and blood vessel invasion (p = 0.0222) in colorectal cancer, while low PLAP expression was found to be associated with advanced pT stage in endometroid carcinoma of the endometrium (p = 0.0043). Here, ALPP is linked to colorectal cancer.