Finally, Western blotting analysis showed that △TBC1 could not promote the expression of CyclinB1, CyclinD1, CDK2, CDK6, RhoA, RHOC, MMP2, β1 integrin, p‐FAK, p‐MEK and p‐ERK in NSCLC cells (Figure S1H). The gene discussed is CDK2; the disease is non-small cell lung carcinoma.