Immunoblotting analysis of the background expression level of FBP1 in 12 ovarian cancer cell lines showed that the expression level of FBP1 was lower in A2780 and SKOV3 cells (Supplementary Fig. 2A) and higher in OVCA433 and OVCA420, so these four cell lines were selected for further experiments. Here, FBP1 is linked to ovarian cancer.