FBP1 and neoplasm: Low-FBP1 mRNA expression was also found to be correlated with significantly worse OS (n = 1656, P = 2.5e−05) and DFS (n = 1435, P = 7.3e−05, Supplementary Fig. 1A) in an independent cohort available in the KMplot database (http://kmplot.com) [18], and further stratified analyses showed the same results among patients with advanced tumor stage (Supplementary Fig. 1B).