We then compared the mRNA levels of key m6A writers (METTL3, METTL14, and WTAP), erasers (ALKBH5 and FTO), and readers (YTHDF1, YTHDF2, IGF2BP1, IGF2BP2, and IGF2BP3) in 25 pairs of CRC and paired normal colorectal tissues by RT-qPCR (Fig. 1b). The gene discussed is YTHDF2; the disease is colorectal carcinoma.