Furthermore, data from large B-cell lymphoma patient datasets revealed a correlation of MYC and CXCR4 expression and an increase of CXCR4 expression in patient samples with translocation of MYC further supporting a regulation of CXCR4 by MYC in a B-cell oncogenic context. This evidence concerns the gene CXCR4 and B-cell non-Hodgkin lymphoma.