MR1 and neoplasm: Furthermore, following NK cell depletion B6-MAITcast MR1−/− and B6-MAITcast MR1 WT mice exhibited a similar metastatic burden following B16F10 tumor challenge, indicating that the enhanced protection exhibited by B6-MAITcast MR1−/− mice is NK cell dependent (Fig. 1f and Supplementary Fig. 1f).