However, the expression of NK cell receptors DNAM-1, CD96 and TIGIT, which contribute to NK cell-mediated anti-tumor function36, was similar on NK cells from B6-MAITcast MR1 WT and B6-MAITcast MR1−/− mice, while a slight decrease in NKG2D expression on NK cells from B6-MAITcast MR1−/− mice was observed (Supplementary Fig. 1b). Here, TIGIT is linked to neoplasm.