ENC1 and breast cancer: Interestingly, by sequencing the SE within the gene-desert region based on H3K27ac enrichment, we identified an approximately 10-kb SE region of ENC1 (ENC1-SEdistal, a region approximately 60 kb upstream of ENC1) in MCF-7 (human BC cell line), HCT116 (human bladder cell line), and PANC-1 (human pancreatic cancer cell line).