Among all the RBPs (HNRNPU, HNRNPK, RBM5, HNRNPLL, HNRNPH1, HNRNPM, HNRNPA2B1) screened, only SRSF7 (also known as 9G8) was substantially upregulated in hypoxia-treated breast cancer cells (Fig. 5A, B). The gene discussed is HNRNPM; the disease is breast cancer.