FHL1 and Fabry disease: HCM is a hereditary myocardial disease in the majority of cases where autosomal dominant sarcomere protein mutations with regard to myofilament encoding are recognized in roughly 35% to 60% of patients and non-sarcomeric genetic mutations representing particular phenotypes such as Fabry disease (GLA gene) and FHL1-related diseases (FHL1 gene), have been identified in a considerable scale of sufferers, together with reported 25% of children [6].