Our data suggest that the presence of exuberant inflammatory infiltrate in TNBC is associated with PD-L1 expression both in the tumor itself and in the tumor stroma, as well as with enrichment for T lymphocytes (CD8+ and CD4+), which may make these tumors important targets for treatment with PD-1 or PD-L1 inhibitors. This evidence concerns the gene CD8A and neoplasm.