TNF and obesity due to melanocortin 4 receptor deficiency: The most important factors of gender, BMI, obesity and occurrence of OSA as well as OSA severity in terms of AHI and ODI, distribution of sleepy vs. non-sleepy OSA phenotypes, ESS score and circulating TNF-α levels were similar in both groups, which confidently supports the concept that the current study population was representative of the whole RICCADSA cohort.