In a case series, Mansouri et al. showed regression of adenomyosis on magnetic resonance imaging (MRI) after treatment with a course of oral contraceptive pills in one patient and resolution of adenomyosis on imaging and of chronic pelvic pain clinically after treatment with leuprolide acetate, a GnRH agonist, in 3 other patients [17]. Here, GNRH1 is linked to adenomyosis.