GH1 and Prader-Willi syndrome: Based on our data on the combined effect of growth hormone treatment and multidisciplinary care, supported by previously reported beneficial effects of GH treatment alone in both children and adults [43,44,45,46,47,48,49,50,51,52,53,68,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,89], we support the pledge by Hoybye et al. for general approval of growth hormone treatment in adults with PWS [94].