Another example of geographical differences regarding the composition of T1D children microbiome is the study conducted in the Northern area of China where children newly diagnosed with T1D (<6 months) showed an intestinal microbiota enriched with the genus Blautia that was also correlated with the levels of HbA1c, T1D autoantibodies, and titers of tyrosine phosphatase autoantibodies (IA-2) [19]. This evidence concerns the gene PTPRN and type 1 diabetes mellitus.