This disease mainly consists of hereditary ATTR (ATTRv; v stands for variant) amyloidosis, alternatively known as familial amyloid polyneuropathy, and wild-type ATTR (ATTRwt) amyloidosis, also known as senile cardiac or systemic amyloidosis, based on the presence or absence of a mutation in TTR [6]. The gene discussed is TTR; the disease is familial amyloid neuropathy.