The pharmacological effect of S. dendroideum in the process of corneal scar formation in a pterygium model was evaluated, and the follow-up of the evolution of the scarring process, allowed to define that the treatment with S. dendroideum had an immunomodulatory effect by decreasing TNF-α, IL-1α, and maintaining the level of IL-10 expression, without difference with respect to the healthy control, demonstrating that traditional medical use of S. dendroideum sap to treat pterygium is fully justified by its compound composition. The gene discussed is IL10; the disease is pterygium.