Since PDGFRα + fibroblasts also contribute to collagen deposition in the bleomycin-induced pulmonary fibrosis model [21], we also performed double staining of PDGFRα and vimentin, and results showed that Fed treatment decreased the PDGFRα + fibroblasts compared with that in the BLM group. This evidence concerns the gene PDGFRA and pulmonary fibrosis.