In a previous study, Cao et al. [33] suggested that surfactin induces apoptosis in human breast cancer MCF-7 cells through a ROS/JNK-mediated mitochondrial/caspase pathway, and that the surfactin has notable anti-tumor effects on MCF-7 cells; however, there was no obvious cytotoxicity on normal cells. The gene discussed is MAPK8; the disease is breast cancer.