By injection of B6 mouse melanoma cells (labeled with GFP or RFP) in the neural tube of 3 dpf transgenic embryos ((Tg(fli1a:EGFP, Tg(mpeg1:mcherry), Tg(mpx:GFP)) [33,119,153], they were able to observe tumor growth, angiogenesis, and accumulation of macrophages, but not neutrophils, within the tumor at 10 dpf. Here, MPEG1 is linked to neoplasm.