Similar results were obtained by Sanderson et al. using the Tg(irg1:EGFP)/Tg(mpeg1:mCherry) transgenic line, in which irg1 specifically labeled M1-like macrophages upon LPS inoculation or M2-like macrophages upon injection of human metastatic breast cancer cells [35]. The gene discussed is ACOD1; the disease is breast cancer.