The unique ability of CCR7 to coordinate the meeting between activated dendritic cells (DCs) and various T cell subsets, including naïve, regulatory, and memory T cells, places CCR7 and its ligands in control of a central immune hub effectively controlling the onset of a diverse set of immune responses depending on the conditions, including inflammation, tolerance, memory, and autoimmunity [3]. Here, CCR7 is linked to Autoimmunity.