GALK1 and colorectal cancer: We also noticed that GALK1, which is beside ITGB4, may be one of the potential target genes of the colorectal-cancer-specific enhancer that is shown in Figure 6A. HiChIP data indicated interactions between the colorectal-cancer-specific enhancer and GALK1, and RNA-seq analysis showed upregulation (fold change = 1.97; q = 7.76 × 10−49) of GALK1 in colorectal cancer tissue compared to that in normal colon tissue.