HiChIP data showed that ITGB4 is regulated by a colorectal-cancer-specific enhancer (Figure 6A), and RNA-seq data showed that ITGB4 is upregulated (fold change = 2.31) in colorectal cancer tissue, suggesting the regulation of ITGB4 by colorectal-cancer-specific enhancers. This evidence concerns the gene ITGB4 and colorectal cancer.