In cervical, HNSCC and non-small cell lung cancer (NSCLC) cells, IL-6 induces a similar pro-mesenchymal morphology, cell scattering, motility and invasion, and decreases E-cadherin and increases N-cadherin and vimentin levels in vitro [94] and in xenografts in nude mice [45,79]. The gene discussed is CDH2; the disease is non-small cell lung carcinoma.