In summary, in November 2011, vitamin D insufficiency associated with higher PTH (Table 2) and CTX values (Table 2 and Figure 6), and, in December 2018, all the BTMs (s-BSAP, P-OC, s-CTX, and U-NTX) values were increased (Table 2 and Figure 6). The gene discussed is CYP27A1; the disease is vitamin D deficiency.