HSP90B2P and neoplasm: As previously outlined, novel hypotheses and relevant therapeutic and diagnostic strategies include the alteration of HSP function, potential manipulation of “oncomiR” expression through the addition of 2-O-methyl or locked nucleic acid oligonucleotides for the therapeutic inactivation of the oncogenic impact of these targets, as well as other novel strategies to enhance tumour suppressors or reduce oncogenic miRNA expression patterns.