Furthermore, the study by Lin et al. in ESCC demonstrated that the hazard ratio (HR) was higher for patients with tumour samples showing >50% of cells stained for HLA-G vs. no staining (HR = 3.02, p-value ≤ 0.001) opposed to patients with 1–50% staining vs. no staining (HR = 2.02, p-value = 0.01) [32]. The gene discussed is HLA-G; the disease is esophageal squamous cell carcinoma.