Proinflammatory cytokines and chemokines secreted by keratinocytes, such as TNF-α, IFN-γ, IL-1β, IL-6, IL-8, TARC (CCL17), MDC (CCL22), and RANTES, play a very important role in dermatitis [25,26,27]. This evidence concerns the gene CXCL8 and skin disorder.