On the other hand, lymphocytes obtained from T2DM showed a merged collection “small colony” of cells that were uniformly distributed with an enlarged size, high nuclear/cytoplasmic ratio and irregular nuclear contour, with membrane vesicles and marked mTOR fluorescence intensity (+++) in the cytoplasm and nucleus along with faint GLUT4 expression (+). This evidence concerns the gene MTOR and type 2 diabetes mellitus.