The hypomethylation of lncRNA EPIC1 (epigenetically induced lncRNA1) upregulates its expression, and overexpression of EPIC1 is correlated to poor survival outcomes in luminal B breast cancer, and was further revealed to promote tumorigenesis through interacting with MYC to increase the occupation of MYC target genes [116]. The gene discussed is EPIC1; the disease is breast carcinoma.