In addition to enrichment for keratins found in normal spheroid stem cells (KRT13, 23, 80, 78, and 4), a group of other keratin genes that includes KRT10, 19, 6, 75, 16, 79, 3, and 82 were enriched in the cSCs relative to the non-cSC population of tumor spheroids. This evidence concerns the gene KRT10 and neoplasm.