HSPA9 and chromosome-type aberration frequency: In addition to mortalin, mutations in GLRX5 (glutaredoxin 5) and ABCB7 (ATP-binding cassette transporter B7) were also shown to cause non-syndromic and syndromic forms of CSA, respectively [263,264], along with recently found aberrations in mitochondrial HSCB (heat shock cognate B), which is the partner of mortalin in ISC formation [265].