During inflammation or infection, blood circulating monocytes that are normally known to express receptors for Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF), Macrophage-Colony Stimulating Factor (M-CSF), and Interleukin-4 (IL-4), other differentiation, and chemoattractant molecules tend to invade tissues and are attracted to the site of inflammation, where they are subsequently differentiated into moDCs. The gene discussed is CSF2; the disease is infection.