Most ALS cases are sporadic (sALS), while approximately 5–10% are familial (fALS), and the most prevalent mutated genes are ‘chromosome 9 open reading frame 72′ (C9orf72), ‘superoxide dismutase 1′ (SOD1), ‘fused in sarcoma’ (FUS), or ‘Tar DNA-binding protein 43′ (TDP-43) [2,3,4]. The gene discussed is FUS; the disease is amyotrophic lateral sclerosis.