In fact, patients with advanced fibrosis and cirrhosis would increase their ANGPTL-4 serum concentration by approximately 31 units, in comparison with the mildly fibrotic patients (95% C.I. = 8.2 to 54.9, p-value = 0.009 for advanced fibrosis, and 95% C.I. = 10.3 to 53.0, p-value = 0.004 for cirrhosis). This evidence concerns the gene ANGPTL4 and Cirrhosis.