In particular, CD3+ CD4+ helper T (Th) cells and CD3+ CD8+ suppressor T cells were detected below normal levels in patients with COVID-19, and CD3+ CD4+ CD45RO+ memory Th cells and CD3+ CD8+ CD28+ cytotoxic suppressor T cells were found to be decreased in severe COVID-19 patients as compared to non-severe patients in Wuhan, China [36]. The gene discussed is CD4; the disease is COVID-19.