A recent study also showed that overexpression of TILRR in BT474, a human breast tumor cell line, significantly potentiates the expression of immune and inflammation-associated genes, including IL-6, IL-8/CXCL8, IP-10 (interferon gamma-induced protein 10)/CXCL10, MCP-1/CCL2, and RANTES/CCL5 [58]. Here, CXCL10 is linked to breast neoplasm.