Hayakawa et al. (2020) found that curcumin could augment antitumor T cell responses by inhibiting STAT3 activated cancer cells and dendritic cells as well as showed synergistic antitumor effect with anti-PD-1/PD-L1 antibodies leading to enhance anticancer immune responses and induction of tumor cell death [30]. This evidence concerns the gene STAT3 and cancer.