Although Arg1 was induced by Salmonella infection in BMDM in vitro and in spleens in vivo, genetic or pharmacological inhibition of ARG1 neither resulted in changes in Salmonella counts after 72 h of infection in various tissue compartments nor in alterations of the expression of several cytokines (Il-6, Il-10 or Tnf) regulating anti-microbial effector pathways. The gene discussed is ARG1; the disease is infection.