After adjustment for other clinicopathological variables, including gender, age, tumor stage, hepatitis etiology, and α-fetoprotein level, low Eg5 expression remained an independent predictor of better OS (hazard ratio (HR) 0.377, p < 0.001) and DFS (HR 0.334, p < 0.001; Table 2). This evidence concerns the gene KIF11 and Hepatitis.