With TGF-β signaling having an important role in various kidney diseases [48], and with recent reports characterizing the crosstalk between miRNA and TGF-β pathways [49,50,51], it is plausible that TGF-β acts on melatonin-affected miRNA network to impact the fibrotic cellular processes, while being under the influence of melatonin. Here, TGFB1 is linked to kidney disorder.