These include CCL2, CCL4, CXCL4, CXCL8, CXCL10, CCL3, IL-1β, IL-6, CXCL2, TNF-α, interferon-gamma (INF-γ), IL-1α, IL-12, IL-17A, IL-15, IL-10, IL1-RA, CCL20, vascular endothelial growth factor (VEGF), IL-13, IL-31, IL-33, CXCL9, IL-9, CCL28 and granulocyte-colony stimulating factor (G-CSF) [5,25,26,27,28,29,30,31,32,33,34,35,36,37,38]. This evidence concerns the gene IL1A and rheumatoid arthritis.